From Quito by Bus:
Buses regularly depart from Quito's Terminal Terrestre, specifically the Carcelén Terminal, which is the most common departure point for Otavalo. Services run frequently, about every 10 to 15 minutes, from 5 AM to 8 PM. The journey typically takes between 1 hour 22 minutes and 2 hours 53 minutes. Fares generally range from $2 to $5 per person.