By Air (to Calama then transfer to San Pedro de Atacama):
The quickest method involves flying to Calama's El Loa International Airport (CJC). Daily flights from Santiago (SCL) are available with airlines like LATAM, Sky Airline, and JetSmart, typically taking 1 hour 45 minutes to 2 hours 15 minutes. Fares can range from approximately $20 to $194 USD for a one-way trip.